HOME » 教室業績 » 著書・論文

平成28年度 教室業績 著書・論文

  • Kazuyuki Ueno, Masaki Shimizu, Tadafumi Yokoyama, Sayaka Ishikawa, Yuko Tasaki, Natsumi Inoue, Naotoshi Sugimoto, (Kazuhide Ohta : Department of Pediatrics, Kanazawa Medical Center, Kanazawa, Japan), Akihiro Yachie.
  • Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis.
  • Clinical and experimental nephrology. Vol.19,No.2,p264-70,2015,04
  • (教室業績第2172号)
  • (Tamaki Kato: Department of Pediatrics, National Defense Medical College, Tokorozawa, Saitama, Japan),(Elena Crestani : Division of Immunology, Children’s Hospital Boston, Harvard Medical School, Boston, MA, USA),(Chikako Kamae, Kenichi Honma),(Tomoko Yokosuka : Department of Hemato-oncology/Regeneration Medicine, Kanagawa Children’s Medical Center, Yokohama, Kanagawa, Japan), (Takeshi Ikegawa : Department of Pediatrics, Yokohama Rosai Hospital, Yokohama, Kanagawa, Japan),(Naonori Nishida, Hirokazu Kanegane : Department of Pediatrics, University of Toyama, Toyama, Japan), Taizo Wada, Akihiro Yachie,(Osamu Ohara : Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan. Department of Technology Development, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan), (Tomohiro Morio : Department of Pediatrics, Tokyo Medical and Dental University(TMDU), Bunkyo-ku, Tokyo), (Luigi D. Notarangelo),(Kohsuke Imai),(Shigeaki Nonoyama).
  • RAG1Deficiency May Present Clinically as Selective IgA Deficiency.
  • Journal of clinical immunology. Vol.35,No.3,p280-8,2015,04.doi:10.107/s 10875-015-0146-4.Epub 2015 Mar 6.
  • (教室業績第2173号)
  • Michio Yasunami, Hitomi Nakamura : Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan), (Kazunaga Agematsu : Department of Infection and Host Defense, Graduate School of Medicine, Shinshu University, Matsumoto, Japan),(Akinori Nakamura, Masahide Yazaki, Dai Kishida : Department of Medicine(Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan), Akihiro Yachie, Tomoko Toma,(Junya Masumoto : Department of Pathogenomics, Ehime University Graduate School of Medicine, To-on, Japan),(Hiroaki Ida : Department of Rheumatology, Kurume University School of Medicine, Kurume, Japan),(Tomohiro Koga, Atsushi Kawakami : First Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan), (Katsumi Eguchi: Department of Rheumatology, Sasebo City General Hospital, Sasebo, Japan),(Hiroshi Furukawa : Department of Rheumatology, National Hospital Organization Sagamihara Hospital, Sagamihara, Japan), (Tadashi Nakamura : Department of Rheumatology, Kumamoto Shinto General Hospital, Kumamoto, Japan), (Minoru Nakamura, Kiyoshi Migita : Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Omura, Japan).
  • Identification of Disease-Promoting HLA Class I and Protective Class II Modifiers in Japanese Patients with Familial Mediterranean Fever.
  • PloS one. Vol.10,No.5,e0125938,2015,05,14.doi:10.1371/journal.pone. 0125938.eCollection 2015.
  • (教室業績第2174号)
  • (Xi Yang, Akihiro Hoshino : Department of Pediatrics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan),(Takashi Taga, Tomoaki Kunitsu, Yuhachi Ikeda : Department of Pediatrics, Shiga University of Medical Science,Otsu, Japan),(Takahiro Yasumi : Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan),(Kenichi Yoshida : Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan), Taizo Wada,(Kunio Miyake, Takeo Kubota: Department of Epigenetic Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan),(Yusuke Okuno, Hideki Muramatsu : Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan), (Yuichi Adachi),(Satoru Miyano : Laboratory of DNA Information Analysis, Human Genome Center, Institute ofMedical Science, The University of Tokyo, Tokyo, Japan ; Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan),(Seishi Ogawa),(Seiji Kojima), (Hirokazu Kanegane : Department of Pediatrics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University of Tokyo, Tokyo, Japan).
  • A female patient with incomplete hemophagocytic lymphohistiocytosis caused by a heterozygous XIAP mutation associated with non-random X-chromosome inactivation skewed towards the wild-type XIAP allele.
  • Journal of Clinical Immunology. Vol.35,No.3,p24-248,2015,04
  • (教室業績第2175号)
  • (Nomura K, Kanegane H, Otsubo K : Department of Pediatrics, Graduate School of Medicine, University of Toyama, Japan), (Wakiguchi H : Department of Pediatrics, Medical Science Cluster, Research and Education Faculty, Kochi University, Nankoku, Japan), (Noda Y : Department of Pediatrics, Kansai Medical University, Hirakata, Japan), Kasahara Y, (Miyawaki T).
  • Autoimmune lymphoproliferative syndrome mimicking chronic active Epstein-Barr virus infection.
  • International journal of hematology Vol.93,No.6,p760-764,Epub 2011 May 28
  • (教室業績第1988号)
  • Mondo Kuroda, Masaki Shimizu, Natsumi Inoue, Iku Ikeno, Hiroyasu Nakagawa, Ayano Yokoi,(Yo Niida : Divisions of Genomic Medicine, Department of Advanced Medicine, Medical Research Institute, Kanazawa Medical University, Uchinada, Japan), (Michio Konishi : Department of Pediatrics, Tonami General Hospital, Tonami, Japan),(Hisashi Kaneda : Department of Pediatrics, Toyama City Hospital, Toyama, Japan),(Noboru Igarashi : Department of Pediatrics, Toyama Prefectural Central Hospital, Toyama, Japan), (Junya Yamahana : Division of Nephrology, Toyama Prefectural Central Hospital, Toyama, Japan), (Hiromichi Taneichi, Hirokazu Kanegane: Department of Pediatrics, Graduate School of Medicine, University of Toyama, Toyama, Japan), (Mika Ito, Shigeru Saito : Department of Obstetrics and Gynecology, School of Medicine, University of Toyama, Toyama, Japan), (Kengo Furuichi, Takashi Wada : Division of Nephrology, Kanazawa University Hospital, Kanazawa, Japan), (Masaru Nakagawa, Hitoshi Yokoyama : D i v i s i o n o f N e p h r o l o g y , K a n a z a w a M e d i c a l U n i v e r s i t y , K a n a z a w a , J a p a n ), Akihiro Yachie.
  • Serum tau protein as a marker of disease activity in enterohemorrhagic Escherichia coli O1-induced hemolytic uremic syndrome.
  • Neurochemistry International. Vol.85-86,p24-30.2015,06-07
  • (教室業績第2176号)
  • Taizo Wada, (Tadayuki Akagi : Department of Stem Cell Biology, Institute of Medical, Pharmaceutical and Health Sciences, School of Medicine, Kanazawa University, Kanazawa, Japan), Masahiro Muraoka, Tomoko Toma, (Kenzo Kaji : Department of Dermatology, Komatsu Municipal Hospital, Komatsu, Japan), (Kazunaga Agematsu: Department of Infection and Host Defense, Shinshu University Graduate School of Medicine, Matsumoto, Japan),(H. Phillip Koeffler: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles School of Medicine, Los Angeles, CA ; and Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore), (Takashi Yokota),Akihiro Yachie.
  • A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency.
  • The Journal of Immunology. Vol.195,No.1,p80-86,2015,07,01.doi:10.4049/ jimmunol.1402.Epub 2015 May 27.
  • (教室業績第2177号)
  • 清水 正樹(金沢大学医薬保健研究域医学系小児科).
  • 【小児リウマチ性疾患の最新治療】若年性特発性関節炎 マクロファージ活性化症 候群の治療(解説/特集).
  • 小児科診療(0386-9806)Vol.78,No.8,p1063-1067,2015,08
  • (教室業績第2178号)
  • 谷内江昭宏.
  • 【家族性腫瘍学-家族性腫瘍の最新研究動向-】症候群 Autoimmune lymphoproliferative syndrome(ALPS)(自己免疫性リンパ増殖症候群).
  • 日本臨床(047-1852)Vol.73 増刊6 家族性腫瘍学,p53-58,2015,08
  • (教室業績第2179号)
  • 石川さやか,清水 正樹,井上なつみ,田! 優子,上野 和之,(濱口 儒人:金沢 大学医薬保健研究域医学系皮膚科学),谷内江明宏.
  • TNF 阻害薬治療中に乾癬様皮疹を呈した若年性特発性関節炎の1例(原著論文/ 症例報告).
  • 小児リウマチ Vol.6,No.1,p39-42,2015,08
  • (教室業績第2180号)
  • 石川さやか,清水 正樹,井上なつみ,田﨑優子,上野 和之,(藤田 健司, 加畑 多文:金沢大学附属病院整形外科),谷内江明宏.
  • 特発性股関節軟骨融解の1例.
  • 小児リウマチ Vol.6,No.1,p73-76,2015,08
  • (教室業績第2181号)
  • 清水 正樹,(竹本 裕子:金沢大学附属病院眼科),高倉麻衣子,井上なつみ, 田﨑優子,石川さやか,上野 和之,谷内江昭宏.
  • 治療抵抗性若年性特発性関節炎関連ぶどう膜炎に対するアダリムマブの有用性(原 著論文/症例報告).
  • 小児リウマチ Vol.6,No.1,p3-38,2015,08
  • (教室業績第2182号)/li>
  • 田﨑優子,清水 正樹,井上なつみ,石川さやか,上野 和之,谷内江昭宏.
  • 全身型若年性特発性関節炎に合併するマクロファージ活性化症候群における Angiopoietin の調節異常(原著論文).
  • 小児リウマチ Vol.6,No.1,p17-2,2015,08
  • (教室業績第2183号)
  • 清水 正樹,(梅林 宏明:宮城県立こども病院リウマチ科),(井上祐三朗:千葉大学 小児病態学),(笠井 和子:兵庫県立こども病院リウマチ科),(金子 詩子:新潟大学 小児科),(菊地 雅子:横浜市立大学附属病院小児科),(木澤 敏毅:北海道北辰病院 小児科),(北川 好郎:愛知医科大学医学部小児科),(久保田知洋:鹿児島大学病院小児 診療センター),(鈴木 一雄:東海大学医学部付属病院大磯病院小児科),(中岸 保夫: 兵庫県こども病院リウマチ科),(橋本 邦生:長崎大学病院小児科),(原 良紀:横 浜市立大学附属病院小児科),(安村 純子:広島大学病院小児科),(山崎 雄一:鹿児 島大学病院小児診療センター).
  • 若年性特発性関節炎に対するメトトレキサート治療の現状 中堅小児リウマチ医の 会におけるアンケート調査(原著論文).
  • 小児リウマチ Vol.6,No.1,p23-27,2015,08
  • (教室業績第2184号)
  • 谷内江昭宏.
  • 【原発性免疫不全症候群 アップデート】原発性免疫不全症 総論(解説/特集).
  • アレルギー・免疫(134-6932)Vol.2,No.9,p172-178,2015,08
  • (教室業績第2186号)
  • Naotoshi Sugimoto, Hue Leu, Natsumi Inoue, Masaki Shimizu, Tomoko Toma, Mondo Kuroda, Takekatsu Saito, Taizo Wada, Akihiro Yachie.
  • The critical role of lipopolysaccharide in the upregulation of aquaporin4in glial cells treated with Shiga toxin.
  • Journal of biomedical science. Vol.18,No.2,p78,2015,09.doi:10.186/s 12929-015-0184-5.
  • (教室業績第2187号)
  • Maiko Takakura, Masaki Shimizu, Natsumi Inoue, Yuko Tasaki, Sayaka Ishikawa, (Kazuhide Ohta : Department of Pediatrics, Kanazawa Medical Center, Kanazawa, Japan), Akihiro Yachie.
  • Iodine-induced non-autoimmune hypothyroidism in a patient with steroid- resistant nephrotic syndrome.
  • Pediatrics international. Vol.57,No.5,p105-6,2015,10.doi:10.1/ped. 12759.
  • (教室業績第2188号)
  • Masaki Shimizu,(Yasuo Nakagishi : Department of Pediatric Rheumatology, Hyogo Prefectural Kobe Children’s Hospital, Kobe, Hyogo, Japan), Natsumi Inoue, (Mao Mizuta), (Giyo Ko, Yutaka Saikawa : Department of Pediatrics, School of Medicine, Kanazawa Medical University, Uchinada, Japan),(Tomohiro Kubota, Yuichi Yamasaki, Syuji Takei : Department of Pediatrics, School of Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan), Akihiro Yachie.
  • Interleukin-18 for predicting the development of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
  • Clinical Immunology. Vol.160,No.2,p27-281,2015,10
  • (教室業績第2189号)
  • (Takeshi Sato, Koji Muroya, Yumi Asakura, Department of Endocrinology and Metabolism , Kanagawa Children ’s Medical Center , Yokohama , Japan ), Akihiro Yachie, (Gen Nishimura : Department of Radiology, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan),(Noriko Aida : Department of Radiology, Kanagawa Children’s Medical Center, Yokohama, Japan), (Jiro Machida : Department of Orthopedic Surgery, Kanagawa Children’s Medical Center, Yokohama, Japan),(Yukichi Tanaka : Department of Pathology, Kanagawa Children’s Medical Center, Yokohama, Japan),(Tomonobu Hasegawa),(Masanori Adachi).
  • Polyostotic osteolysis and hypophosphatemic rickets with elevated serum fibroblast growth factor23:A case report.
  • American Journal of Medical Genetics Part A. Vol.167,No.10,p2430-2434, 2015,10
  • (教室業績第2190号)
  • (Yusuke Okuno : Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.),(Akihiro Hoshino: Department of Pediatrics, Graduate School of Medicine, University of Toyama, Toyama, Japan.),(Hideki Muramatsu, Nozomu Kawashima, Xinan Wang),(Kenichi Yoshida : Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.), Taizo Wada, (Masaharu Gunji : Department of Pathology, Japanese Red Cross Nagoya first Hospital, Nagoya, Japan.), Tomoko Toma,(Tamaki Kato : Department of Pediatrics, National Defense Medical College, Saitama, Japan.),(Yuichi Shiraishi : Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.), (Atsuko Iwata, Toshinori Hori, Toshiyuki Kitoh : Department of Pediatrics, Aichi Medical University School of Medicine, Nagakute, Japan.), (Kenichi Chiba, Hiroko Tanaka), (Masashi Sanada),(Yoshiyuki Takahashi),(Shigeaki Nonoyama),(Masafumi Ito), (Satoru Miyano : Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan ; Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo , Tokyo , Japan . ), ( Seishi Ogawa ), ( Seiji Kojima ), (Hirokazu Kanegane: Department of Pediatrics, Graduate School of Medicine, University of Toyama, Toyama, Japan. ; Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.).
  • Late-Onset Combined Immunodeficiency with a Novel IL2RG Mutation and Probable Revertant Somatic Mosaicism.
  • Journal of clinical immunology. Vol.35,No.7,p610-4,2015,10.doi:10.107/s 10875-015-0202-0.Epub 2015 Sep 26.
  • (教室業績第2191号)
  • 谷内江昭宏.
  • 【小児疾患診療のための病態生理2 改訂第5版】免疫不全 二次性免疫不全症(解 説/特集).
  • 小児内科(0385-6305)Vol.47 増刊,p659-63,2015,1
  • (教室業績第2192号)
  • 清水 正樹(金沢大学医薬保健研究域医学系小児科).
  • 【小児疾患診療のための病態生理2 改訂第5版】リウマチ性疾患とその周辺疾患 マクロファージ活性化症候群(解説/特集).
  • 小児内科(0385-6305)Vol.47 増刊,p91-914,2015,11
  • (教室業績第2193号)
  • Hitoshi Tajiri : Osaka General Medical Center, Osaka, Japan), (Junichiro Nishi : Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan), (Kosuke Ushijima : Kurume University Medical Center, Kurume, Japan), (Toshiaki Shimizu : Juntendo University Graduate School of Medicine, Tokyo, Japan), (Takashi Ishige : Gunma University Graduate School of Medicine, Gunma, Japan), Masaki Shimizu, (Hideo Tanaka : Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan),(Stephen Brooks : Department of Microbiology & Immunology, State University of New York at Buffalo, Buffalo, NY, USA).
  • A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection.
  • International Journal of Antimicrobial Agents. Vol.46,No.5,p586-589, 2015,11
  • (教室業績第2194号)
  • Masaki Shimizu, (Yasuhito Hamaguchi : Department of Dermatology, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan), Sayaka Ishikawa, Kazuyuki Ueno, Akihiro Yachie.
  • Successful treatment with tocilizumab of a psoriasiform skin lesion induced by etanercept in a patient with juvenile idiopathic arthritis.
  • Modern rheumatology. Vol.25,No.6,p972-3,2015
  • (教室業績第2195号)
  • 和田 泰三.
  • 【小児疾患診療のための病態生理2 改訂第5版】免疫不全 その他の複合型免疫 不全症(Omenn 症候群を含めて).
  • 小児内科(0385-6305)Vol.47 増刊,p679-685,2015,11
  • (教室業績第2196号)
  • (Huan-Ting Lin : Division of Stem Cell Therapy, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan.), (Hideki Masaki : Japan Science Technology Agency, Exploratory Research for Advanced Technology Nakauchi Stem Cell and Organ Regeneration Project, Tokyo, Japan.), (Tomoyuki Yamaguchi : Division of Stem Cell Therapy, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan ; Japan Science Technology Agency, Exploratory Research for Advanced Technology Nakauchi Stem Cell and Organ Regeneration Project, Tokyo, Japan.), Taizo Wada, Akihiro Yachie,(Ken Nishimura: Research Center for Stem Cell Engineering, National Institute of Advanced, Industrial Science and Technology, Tsukuba, Japan ; Laboratory of Gene Regulation, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.), (Manami Ohtaka, Mahito Nakanishi : Research Center for Stem Cell Engineering, National Institute of Advanced, Industrial Science and Technology, Tsukuba, Japan.),(Hiromitsu Nakauchi),(Makoto Otsu).
  • An assessment of the effects of ectopic gp91phox expression in XCGD iPSC- derived neutrophils.
  • Molecular therapy. Methods & clinical development.2015,12.9;2:15046
  • (教室業績第2197号)
  • Wada T, Toma T, (Yasui M, Inoue M, Kawa K: Department of Hematology/Oncology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan),(Imai K, Morio T : Department of Pediatrics, Tokyo Medical and Dental University, Tokyo, Japan), Yachie A.
  • Different Clinical Phenotypes in 2 Siblings With X-Linked Severe Combined Immunodeficiency.
  • J Investig Allergol Clin Immunol, Vol.26,No.1,p63-65,2016.doi:10.18176/ jiaci.014
  • (教室業績第2198号)
  • Raita Araki, Ryosei Nishimura, Shintaro Mase, Toshihiro Fujiki, Rie Kuroda, Hideaki Maeba, Shoichi Koizumi, Akihiro Yachie, Yo Niida.
  • Effective Prophylaxis Against Various Adverse Events from Mitochondrial Cytochrome b Gene Mutation Triggered by Transplant-Related Chemotherapy and Immunosuppressants.
  • Pediatric Blood & Cancer. Vol.63,No.2,p374,2016,02
  • (教室業績第2199号)
  • 和田 泰三.
  • I【非 IgE 依存性消化管食物アレルギー】Food protein-induced enterocolitis syndrome(FPIES)における便中 EDN の増加(解説/特集).
  • 臨床免疫・アレルギー科 Vol.65,No.2,p136-139,2016,02
  • (教室業績第2200号)
  • 黒田 文人.
  • 【MEDI QUIZ】小児 2歳9カ月男児.痙攣群発,意識障害.
  • 日経メディカル2016年3月号 No.580,p85-86,2016,03,10
  • (教室業績第2201号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect DNA recombination defect 総論(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p49-56,2016,03
  • (教室業績第2202号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect RAG1欠損症/RAG2欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p57-59,2016,03
  • (教室業績第2203号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect DCLRE1C(Artemis)欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p60-61,2016,03
  • (教室業績第2204号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect DNA-PKcs(PRKDC)欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p62-63,2016,03
  • (教室業績第2205号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect Cernunnos(XLF)欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p64-65,2016,03
  • (教室業績第2206号)
  • 谷内江昭宏.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 複合免疫不全症 T-B-重症複合免疫不全症(SCID) DNA recombination defect DNA ligase IV(LIG4)欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p66-67,2016,03
  • (教室業績第2207号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 先天性食細胞機能不全症及び欠損症 好中球運動能の障害 白血球接着不全症1型 (解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p616-618,2016,03
  • (教室業績第2208号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 先天性食細胞機能不全症及び欠損症 好中球運動能の障害 白血球接着不全症2型 (解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p619-620,2016,03
  • (教室業績第2209号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 先天性食細胞機能不全症及び欠損症 好中球運動能の障害 白血球接着不全症3型 (解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p621-622,2016,03
  • (教室業績第2210号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 先天性食細胞機能不全症及び欠損症 好中球運動能の障害 好中球二次(特殊)顆 粒欠損症(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p641-643,2016,03
  • (教室業績第2211号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 免疫調節障害 家族性血球貪食性リンパ組織球(FHL)症候群 色素脱失を伴わ ない FHL 症候群 SH2D1A 欠損症(XLP-1)(解説/特集).
  • 日本臨床(047-1852)別冊免疫症候群III p461-464,2016,03
  • (教室業績第2212号)
  • 和田 泰三.
  • 【免疫症候群(第2版)-その他の免疫疾患を含めて-】原発性免疫不全症候群 免疫調節障害 家族性血球貪食性リンパ組織球(FHL)症候群 色素脱失を伴わ ない FHL 症候群 XIAP 欠損症(XLP-2).
  • 日本臨床(047-1852)別冊免疫症候群III p465-467,2016,03
  • (教室業績第2213号)
学位論文

  • Yasuhisa Sakakibara, Taizo Wada, Masahiro Muraoka, Yusuke Matsuda, Tomoko Toma, Akihiro Yachie.
  • Basophil activation by mosquito extracts in patients with hypersensitivity to mosquito bites.
  • Cancer Science. Vol.106,No.8,p965-971,2015,08
  • (教室業績第2185号)
  • Abstract
  • Hypersensitivity to mosquito bite(s HMB)is a cutaneous disorder belonging to the group of Epstein-Barr virus(EBV)-associated T/natural killer(NK)-cell lymphoproliferative diseases, and is primarily mediated by EBV-infected NK cells. It is characterized by intense local skin reactions accompanied by general symptoms after mosquito bites, and infiltration of EBV-infected NK cells into the bite sites. However, the mechanisms underlying these reactions have not been fully examined. We recently described the activation of circulating basophils by mosquito extracts in vitro in a patient with HMB. To further investigate this finding, we studied four additional patients with HMB. All patients showed typical clinical features of HMB after mosquito bites and they had NK lymphocytosis and high peripheral blood EBV DNA loads. We found evidence of EBV infection in NK cells through in situ hybridization that detected EBV- encoded small RNA-1, and flow cytometry showed HLA-DR expression on almost all NK cells. Basophil activation tests with the extracts of epidemic mosquitoes Culex pipiens pallens and Aedes albopictus showed positive responses to one or both extracts in all samples from patients with HMB, suggesting the presence of mosquito antigen-specific IgE and its binding to basophils. In particular, the extract of Aedes albopictus was able to activate basophils in all available patient samples. These results indicate that basophils and/or mast cells activated by mosquito bites may be involved in initiation and development of severe skin reactions to mosquito bites in HMB.